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Jan 2023   I’m a title. Click to edit me

Jan 2023   I’m a title. Click to edit me.

Jan 2023   I’m a title. Click to edit me.

Jan 2023   I’m a title. Click to edit me.

Jan 2023   I’m a title. Click to edit me.

Jan 2023   I’m a title. Click to edit me.

Jan 2023   I’m a title. Click to edit me.

Jan 2023   I’m a title. Click to edit me.

Journal Publications
Academic Publications 

- Claude Bernard -

Principali pubblicazioni 

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Link to PubMed MyBibliography:

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https://www.ncbi.nlm.nih.gov/sites/myncbi/1t5nVSlZczVQn/bibliography/42576587/public/?sort=date&direction=ascending

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Journal Articles

  1. Mollica A, Pelliccia S, Famiglini V, Stefanucci A, Macedonio G, et al. Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors. J Enzyme Inhib Med Chem. 2017 Dec;32(1):444-451. PubMed PMID: 28097916.

  2. Ferrante C, Recinella L, Locatelli M, Guglielmi P, Secci D, et al. Protective Effects Induced by Microwave-Assisted Aqueous Harpagophytum Extract on Rat Cortex Synaptosomes Challenged with Amyloid β-Peptide. Phytother Res. 2017 Jun 21;PubMed PMID: 28635142.

  3. Locatelli M, Ferrante C, Carradori S, Secci D, Leporini L, et al. Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model. Phytother Res. 2017 Jun;31(6):937-944. PubMed PMID: 28447368.

  4. Iodice P, Ferrante C, Brunetti L, Cabib S, Protasi F, et al. Fatigue modulates dopamine availability and promotes flexible choice reversals during decision making. Sci Rep. 2017 Apr 3;7(1):535. PubMed PMID: 28373651; PubMed Central PMCID: PMC5428685.

  5. Ferrante C, Orlando G, Recinella L, Leone S, Chiavaroli A, et al. Central inhibitory effects on feeding induced by the adipo-myokine irisin. Eur J Pharmacol. 2016 Nov 15;791:389-394. PubMed PMID: 27614130.

  6. Menghini L, Ferrante C, Leporini L, Recinella L, Chiavaroli A, et al. A natural formula containing lactoferrin, Equisetum arvensis, soy isoflavones and vitamin D3 modulates bone remodeling and inflammatory markers in young and aged rats. J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4):985-996. PubMed PMID: 28078844.

  7. Menghini L, Ferrante C, Leporini L, Recinella L, Chiavaroli A, et al. An Hydroalcoholic Chamomile Extract Modulates Inflammatory and Immune Response in HT29 Cells and Isolated Rat Colon. Phytother Res. 2016 Sep;30(9):1513-8. PubMed PMID: 27237110.

  8. Ferrante C, Orlando G, Recinella L, Leone S, Chiavaroli A, et al. Central apelin-13 administration modulates hypothalamic control of feeding. J Biol Regul Homeost Agents. 2016 Jul-Sep;30(3):883-888. PubMed PMID: 27655516.

  9. Leone S, Chiavaroli A, Shohreh R, Ferrante C, Ricciuti A, et al. Increased locomotor and thermogenic activity in mice with targeted ablation of the GHRH gene. Growth Horm IGF Res. 2015 Apr;25(2):80-4. PubMed PMID: 25588992.

  10. Brunetti L, Leone S, Orlando G, Ferrante C, Recinella L, et al. Hypotensive effects of omentin-1 related to increased adiponectin and decreased interleukin-6 in intra-thoracic pericardial adipose tissue. Pharmacol Rep. 2014 Dec;66(6):991-5. PubMed PMID: 25443726.

  11. Menghini L, Leporini L, Pintore G, Ferrante C, Recinella L, et al. A natural formulation (imoviral™) increases macrophage resistance to LPS-induced oxidative and inflammatory stress in vitro. J Biol Regul Homeost Agents. 2014 Oct-Dec;28(4):775-82. PubMed PMID: 25620186.

  12. Leone S, Shohreh R, Manippa F, Recinella L, Ferrante C, et al. Behavioural phenotyping of male growth hormone-releasing hormone (GHRH) knockout mice. Growth Horm IGF Res. 2014 Oct;24(5):192-7. PubMed PMID: 25028079.

  13. Brunetti L, Orlando G, Ferrante C, Recinella L, Leone S, et al. Peripheral chemerin administration modulates hypothalamic control of feeding. Peptides. 2014 Jan;51:115-21. PubMed PMID: 24269538.

  14. Recinella L, Shohreh R, Salvatori R, Orlando G, Vacca M, et al. Effects of isolated GH deficiency on adipose tissue, feeding and adipokines in mice. Growth Horm IGF Res. 2013 Dec;23(6):237-42. PubMed PMID: 24021480.

  15. Brunetti L, Ferrante C, Orlando G, Recinella L, Leone S, et al. Orexigenic effects of endomorphin-2 (EM-2) related to decreased CRH gene expression and increased dopamine and norepinephrine activity in the hypothalamus. Peptides. 2013 Oct;48:83-8. PubMed PMID: 23916912.

  16. Brunetti L, Orlando G, Ferrante C, Recinella L, Leone S, et al. Orexigenic effects of omentin-1 related to decreased CART and CRH gene expression and increased norepinephrine synthesis and release in the hypothalamus. Peptides. 2013 Jun;44:66-74. PubMed PMID: 23538212.

  17. Brunetti L, Chiavaroli A, Cocco A, Ferrante C, Ferrucci A, et al. Synthesis and neuromodulatory effects of TRH-related peptides: inhibitory activity on catecholamine release in vitro. Pharmacol Rep. 2013;65(4):823-35. PubMed PMID: 24145076.

  18. Leone S, Chiavaroli A, Orlando G, Mollica A, Di Nisio C, et al. The analgesic activity of biphalin and its analog AM 94 in rats. Eur J Pharmacol. 2012 Jun 15;685(1-3):70-3. PubMed PMID: 22546229.

  19. Brunetti L, Recinella L, Di Nisio C, Chiavaroli A, Leone S, et al. Effects of visfatin/PBEF/NAMPT on feeding behaviour and hypothalamic neuromodulators in the rat. J Biol Regul Homeost Agents. 2012 Apr-Jun;26(2):295-302. PubMed PMID: 22824756.

  20. Menghini L, Leporini L, Scanu N, Pintore G, Ferrante C, et al. A multiherbal formulation influencing immune response in vitro. Minerva Med. 2012 Feb;103(1):13-21. PubMed PMID: 22278065.

  21. Petrini M, Ferrante M, Ciavarelli L, Brunetti L, Vacca M, et al. Prostaglandin E2 to diagnose between reversible and irreversible pulpitis. Int J Immunopathol Pharmacol. 2012 Jan-Mar;25(1):157-63. PubMed PMID: 22507328.

  22. D'Aurizio E, Sozio P, Cerasa LS, Vacca M, Brunetti L, et al. Biodegradable microspheres loaded with an anti-Parkinson prodrug: an in vivo pharmacokinetic study. Mol Pharm. 2011 Dec 5;8(6):2408-15. PubMed PMID: 22014118.

  23. Valle G, Carmignani M, Brunetti L, Volpe AR. Metformin plus temozolomide-based chemotherapy as adjuvant treatment for WHO grade III and IV malignant gliomas. J BUON. 2011 Oct-Dec;16(4):787; author reply 787-8. PubMed PMID: 22331745.

  24. Brunetti L, Di Nisio C, Recinella L, Chiavaroli A, Leone S, et al. Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat. Peptides. 2011 Sep;32(9):1866-71. PubMed PMID: 21855588.

  25. Verratti V, Brunetti L, Tenaglia R, Chiavaroli A, Ferrante C, et al. Physiological analysis of 8-ISO-PGF2 alpha: a homeostatic agent in superficial bladder cancer. J Biol Regul Homeost Agents. 2011 Jan-Mar;25(1):71-6. PubMed PMID: 21382275.

  26. Brunetti L, Leone S, Chiavaroli A, Orlando G, Recinella L, et al. Cafeteria diet increases prostaglandin E2 levels in rat prostate, kidney and testis. Int J Immunopathol Pharmacol. 2010 Oct-Dec;23(4):1073-8. PubMed PMID: 21244756.

  27. Chiavaroli A, Brunetti L, Orlando G, Recinella L, Ferrante C, et al. Resveratrol inhibits isoprostane production in young and aged rat brain. J Biol Regul Homeost Agents. 2010 Oct-Dec;24(4):441-6. PubMed PMID: 21122283.

  28. Brunetti L, Di Nisio C, Recinella L, Orlando G, Ferrante C, et al. Obestatin inhibits dopamine release in rat hypothalamus. Eur J Pharmacol. 2010 Sep 1;641(2-3):142-7. PubMed PMID: 20553917.

  29. Brunetti L, Menghini L, Orlando G, Recinella L, Leone S, et al. Antioxidant effects of garlic in young and aged rat brain in vitro. J Med Food. 2009 Oct;12(5):1166-9. PubMed PMID: 19857085.

  30. Brunetti L, Leone S, Orlando G, Recinella L, Ferrante C, et al. Effects of obestatin on feeding and body weight after standard or cafeteria diet in the rat. Peptides. 2009 Jul;30(7):1323-7. PubMed PMID: 19397941.

  31. Brunetti L, Orlando G, Recinella L, Leone S, Ferrante C, et al. Glucagon-like peptide 1 (7-36) amide (GLP-1) and exendin-4 stimulate serotonin release in rat hypothalamus. Peptides. 2008 Aug;29(8):1377-81. PubMed PMID: 18502539.

  32. Verratti V, Di Giulio C, Berardinelli F, Tiboni GM, Pellicciotta M, et al. Pampiniform plexus and oxidative stress during chronic hypoxia and hyperoxia. Int J Immunopathol Pharmacol. 2008 Apr-Jun;21(2):353-7. PubMed PMID: 18547479.

  33. Brunetti L, Orlando G, Menghini L, Ferrante C, Chiavaroli A, et al. Ginkgo biloba leaf extract reverses amyloid beta-peptide-induced isoprostane production in rat brain in vitro. Planta Med. 2006 Nov;72(14):1296-9. PubMed PMID: 17022004.

  34. Minelli A, Bellezza I, Grottelli S, Pinnen F, Brunetti L, et al. Phosphoproteomic analysis of the effect of cyclo-[His-Pro] dipeptide on PC12 cells. Peptides. 2006 Jan;27(1):105-13. PubMed PMID: 16137790.

  35. Brunetti L, Orlando G, Ferrante C, Chiavaroli A, Vacca M. Peptide YY (3 -36) inhibits dopamine and norepinephrine release in the hypothalamus. Eur J Pharmacol. 2005 Sep 5;519(1-2):48-51. PubMed PMID: 16095590.

  36. Belli R, Amerio P, Brunetti L, Orlando G, Toto P, et al. Elevated 8-isoprostane levels in basal cell carcinoma and in UVA irradiated skin. Int J Immunopathol Pharmacol. 2005 Jul-Sep;18(3):497-502. PubMed PMID: 16164830.

  37. Brunetti L, Di Nisio C, Orlando G, Ferrante C, Vacca M. The regulation of feeding: a cross talk between peripheral and central signalling. Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):201-12. PubMed PMID: 15888244.

  38. Brunetti L, Orlando G, Recinella L, Michelotto B, Ferrante C, et al. Resistin, but not adiponectin, inhibits dopamine and norepinephrine release in the hypothalamus. Eur J Pharmacol. 2004 Jun 16;493(1-3):41-4. PubMed PMID: 15189762.

  39. Brunetti L, Michelotto B, Orlando G, Recinella L, Di Nisio C, et al. Aging increases amyloid beta-peptide-induced 8-iso-prostaglandin F2alpha release from rat brain. Neurobiol Aging. 2004 Jan;25(1):125-9. PubMed PMID: 14675738.

  40. Nisio CD, Brunetti L, Esposito DL, Recinella L, Orlando G, et al. Desialylated N-CAM and chromatin-derived acidic peptide effects in the hypothalamus. Peptides. 2003 Aug;24(8):1231-6. PubMed PMID: 14612195.

  41. Brunetti L, Recinella L, Orlando G, Michelotto B, Di Nisio C, et al. Effects of ghrelin and amylin on dopamine, norepinephrine and serotonin release in the hypothalamus. Eur J Pharmacol. 2002 Nov 15;454(2-3):189-92. PubMed PMID: 12421646.

  42. Brunetti L, Orlando G, Michelotto B, Recinella L, Di Nisio C, et al. Identification of 8-iso-prostaglandin F(2alpha) in rat brain neuronal endings: a possible marker of membrane phospholipid peroxidation. Life Sci. 2002 Oct 4;71(20):2447-55. PubMed PMID: 12231405.

  43. Brunetti L, Cacciatore I, Di Stefano A, Duprè S, Giorgi A, et al. Synthesis and biological evaluation of a novel pyroglutamyl-modified TRH analogue. Farmaco. 2002 Jun;57(6):479-86. PubMed PMID: 12088063.

  44. Orlando G, Brunetti L, Vacca M. Ritonavir and Saquinavir directly stimulate anterior pituitary prolactin secretion, in vitro. Int J Immunopathol Pharmacol. 2002 Jan-Apr;15(1):65-68. PubMed PMID: 12593790.

  45. Orlando G, Brunetti L, Di Nisio C, Michelotto B, Recinella L, et al. Effects of cocaine- and amphetamine-regulated transcript peptide, leptin and orexins on hypothalamic serotonin release. Eur J Pharmacol. 2001 Nov 2;430(2-3):269-72. PubMed PMID: 11711041.

  46. Cingolani GM, Di Stefano A, Napolitani F, Mosciatti B, Giorgioni G, et al. Synthesis and preliminary pharmacological evaluation of 5-hydroxy- and 5,6-dihydroxy-1,2,3,7,12,12a-hexahydrobenzo[5,6]cyclohepta[1,2,3-ij]isoquinoline derivatives as dopamine receptor ligands. Bioorg Med Chem. 2001 Jun;9(6):1447-58. PubMed PMID: 11408163.

  47. Brunetti L, Orlando G, Michelotto B, Recinella L, Vacca M. Chromatin-derived acidic peptides modulate catecholamine release in the hypothalamus. Peptides. 2001 Jun;22(6):975-8. PubMed PMID: 11390028.

  48. Delfino DV, Salcedo M, Marco BD, Ayroldi E, Nocentini G, et al. Differentiation of Ly49s-positive or -negative natural killer cells is inhibited by anti-H-2b monoclonal antibodies acting at the level of bone marrow progenitors from B6 mice. Cell Growth Differ. 2001 Jan;12(1):51-60. PubMed PMID: 11205745.

  49. Brunetti L, Orlando G, Michelotto B, Recinella L, Vacca M. Cocaine- and amphetamine-regulated transcript peptide-(55-102) and thyrotropin releasing hormone inhibit hypothalamic dopamine release. Eur J Pharmacol. 2000 Dec 8;409(2):103-7. PubMed PMID: 11104823.

  50. Muzii L, Marana R, Brunetti L, Orlando G, Michelotto B, et al. Atypical endometriosis revisited: clinical and biochemical evaluation of the different forms of superficial implants. Fertil Steril. 2000 Oct;74(4):739-42. PubMed PMID: 11020516.

  51. Brunetti L, Orlando G, Michelotto B, Recinella L, Ragazzoni E, et al. A possible prolactin-related adverse effect of certain antineoplastic anthracyclines. Toxicol Lett. 2000 Aug 16;116(3):231-6. PubMed PMID: 10996485.

  52. Nocentini G, Ronchetti S, Bartoli A, Spinicelli S, Delfino D, et al. Identification of three novel mRNA splice variants of GITR. Cell Death Differ. 2000 Apr;7(4):408-10. PubMed PMID: 10836847.

  53. Claudi F, Di Stefano A, Napolitani F, Cingolani GM, Giorgioni G, et al. Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy-2,3, 12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands. J Med Chem. 2000 Feb 24;43(4):599-608. PubMed PMID: 10691686.

  54. Brunetti L, Michelotto B, Orlando G, Vacca M. Leptin inhibits norepinephrine and dopamine release from rat hypothalamic neuronal endings. Eur J Pharmacol. 1999 May 21;372(3):237-40. PubMed PMID: 10395017.

  55. Brunetti L, Orlando G, Michelotto B, Ragazzoni E, Vacca M. Leptin stimulates prostaglandin E2 and F2alpha, but not nitric oxide production in neonatal rat hypothalamus. Eur J Pharmacol. 1999 Mar 26;369(3):299-304. PubMed PMID: 10225366.

  56. Brunetti L, Ragazzoni E, Folchitto G, Vacca M. Neuramide stimulates adrenocorticotropin but not prolactin release from rat pituitary. Pharmacol Res. 1996 Nov-Dec;34(5-6):269-73. PubMed PMID: 9076851.

  57. Muzii L, Marana R, Brunetti L, Romanini ME, Vavala V V, et al. Production of Prostaglandin F2alpha by the Different Forms of Endometriosis. J Am Assoc Gynecol Laparosc. 1996 Aug;3(4, Supplement):S33. PubMed PMID: 9074191.

  58. Muzii L, Brunetti L, Marana R, Margutti F, Vacca M, et al. Low-Dose Aspirin to Prevent Postoperative Adhesion Formation in the Rabbit Model. J Am Assoc Gynecol Laparosc. 1996 Aug;3(4, Supplement):S32-3. PubMed PMID: 9074190.

  59. Brunetti L, Volpe AR, Ragazzoni E, Preziosi P, Vacca M. Interleukin-1 beta specifically stimulates nitric oxide production in the hypothalamus. Life Sci. 1996;58(25):PL373-7. PubMed PMID: 8649215.

  60. Brunetti L, Ragazzoni E, Preziosi P, Vacca M. A possible role for nitric oxide but not for prostaglandin E2 in basal and interleukin-1-beta-induced PRL release in vitro. Life Sci. 1995 Mar 3;56(15):PL277-83. PubMed PMID: 8614237.

  61. Brunetti L, Preziosi P, Ragazzoni E, Vacca M. Effects of vindesine on hypothalamic-pituitary-adrenal axis. Toxicol Lett. 1995 Jan;75(1-3):69-73. PubMed PMID: 7863539.

  62. Brunetti L. Nitric oxide: a gas as a modulator of neuroendocrine secretions. Clin Ter. 1994 Feb;144(2):147-53. PubMed PMID: 8181209.

  63. Brunetti L, Preziosi P, Ragazzoni E, Vacca M. Effects of lipopolysaccharide on hypothalamic-pituitary-adrenal axis in vitro. Life Sci. 1994;54(10):PL165-71. PubMed PMID: 8107506.

  64. Brunetti L, Preziosi P, Ragazzoni E, Vacca M. Involvement of nitric oxide in basal and interleukin-1 beta-induced CRH and ACTH release in vitro. Life Sci. 1993;53(13):PL219-22. PubMed PMID: 7690108.

  65. Navarra P, Pozzoli G, Brunetti L, Ragazzoni E, Besser M, et al. Interleukin-1 beta and interleukin-6 specifically increase the release of prostaglandin E2 from rat hypothalamic explants in vitro. Neuroendocrinology. 1992 Jul;56(1):61-8. PubMed PMID: 1641074.

  66. Pozzoli G, Brunetti L, Navarra P. Production and release of eicosanoids from rat hypothalamic explants in vitro. Pharmacol Res. 1992 Feb-Mar;25 Suppl 1:27-8. PubMed PMID: 1508799.

  67. Brunetti L. [Molecular basis of the communication of the nervous, endocrine and immune systems]. Clin Ter. 1991 Mar 15;136(5):301-20. PubMed PMID: 1645635.

 Books and Chapters

  1. Brunetti L. Droghe naturali e sintetiche. 1 ed. Rome: ISBN 9788892317246; 2016. 236p.

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